A total of 45 people, 27 males and 18 females, tested positive for COVID-19 on Wednesday, September 21, from the 388 tests conducted by laboratories across the island.
The cases consisted of 10 people under the age of 18, and 35 who were 18 years and older.
The number of people in isolation facilities was 33, while 298 were in home isolation.
As at September 21, there were 559 COVID-19 related deaths.
The laboratories conducted 763,308 tests since February 2020, and recorded 102,366 COVID-19 cases (46,303 males and 56,063 females).
Under the National Vaccination Programme for COVID-19, the total number of people with at least one dose is 163,611 (71.6 per cent of the eligible population). The total number of fully vaccinated individuals is 154,630 (57 per cent of the total population or 67.7 per cent of the eligible population). The eligible population represents those people who are 12 years and older.